Diagnostic performance of insulin resistance indices and their association with metabolic outcomes in children with obesity: a 10-year retrospective study from a tertiary pediatric endocrinology center.

Among pubertal participants, the optimal homeostatic model assessment for insulin resistance cut-off values for predicting oral glucose tolerance test-defined insulin resistance were 4.22 in girls and 4.18 in boys.

Insulin resistance was present in 76.3% of participants and was associated with an unfavorable metabolic profile, including higher rates of dysglycemia and hepatic steatosis.

Hepatic steatosis was detected in 63.5% of children and was significantly more common in boys.