Sociodemographic Factors Associated With Later Stage at Diagnosis of Pediatric Germ Cell Tumors: A Report From Children's Oncology Group Registries ACCRN07 and APEC14B1.

Of 1850 patients with germ cell tumors, n = 1316 had extracranial and n = 534 intracranial tumors.

In multivariable models, females had lower odds of distant stage disease diagnosis (extracranial: OR, 0.40; 95% CI, 0.28-0.58 vs. local/regional; intracranial OR, 0.44; 95% CI, 0.24-0.83) than males.

Participants diagnosed between 1998-2009 (OR, 0.52; 95% CI, 0.29-0.68) and 2010-2014 (OR, 0.51; 95% CI, 0.39-0.68) had lower odds of local stage disease than regional or distant stage disease versus 2015-2021.

No family/area factors were significant for females.