Association Between Opioid Use Disorder and Hysterectomy Outcomes.
Opioid use disorder is associated with higher complication rates after inpatient hysterectomy.
Association Between Opioid Use Disorder and Hysterectomy Outcomes.
To evaluate the associations between opioid use disorder (opioid use disorder) and complications, length of stay, and costs of hysterectomy.
This retrospective cohort study evaluated patients with and without opioid use disorder who were aged 18 years or older and underwent hysterectomy.
Adjusted rate ratio: complications were about 18% more likely with opioid use disorder.
The mean age was 48.5 years; 68.6% of the surgeries took place in urban teaching hospitals.
Mean charges were $48,027 and $50,297, respectively (adjusted incidence risk ratio [IRR] 0.96; 95% CI, 0.91-1.01).
The overall mean age was 50.6 years; most hospitals were urban teaching hospitals (74.7%).
Patients with opioid use disorder were admitted for a mean of 4.3 days, compared with 3.2 days for those without opioid use disorder (adjusted IRR 1.32; 95% CI, 1.24-1.41).
This study suggests that patients with opioid use disorder are at higher risk of complication after outpatient and inpatient hysterectomies than patients without opioid use disorder.
Opioid use disorder was also associated with a longer length of stay and increased hospital charges for those who underwent inpatient hysterectomy. These patients may benefit from additional preoperative optimization and education.