Autoimmune encephalitis in older adults: Atypical presentation, therapeutic approaches and implication for diagnostic criteria.

Older adults had a lower prevalence of CSF pleocytosis (p < 0.001).

Older adults with a positive antibody status were less likely to meet probable antibody-negative autoimmune encephalitis clinical consensus criteria (9.5% vs 34.2% p = 0.027).

In terms of treatment and outcome, older adults were less likely to receive second-line immunotherapy (7.1% vs 32.8%, p < 0.001), and have a longer median length of stay (19 vs 10 days p = 0.042).