First Report of Fatal Disseminated Blastomyces percursus Infection in a Liver Transplant Recipient in Iran…

Case reportMycopathologia· Jul 2026

First Report of Fatal Disseminated Blastomyces percursus Infection in a Liver Transplant Recipient in Iran, a Non-endemic Country: A Case Report.

Fereshteh Ghiasvand, Safoura Shakoeinejad, Negar Hemmati … Ali Reza Khosravi

DermatologyCase reportDiagnosisQ1IF 2.9

Gene sequencing showed near-perfect match confirming rare Blastomyces percursus infection

First Report of Fatal Disseminated Blastomyces percursus Infection in a Liver Transplant Recipient in Iran, a Non-endemic Country: A Case Report.

Fereshteh Ghiasvand … Ali Reza Khosravi

Mycopathologia · Jul 2026

Background

Blastomycosis is an invasive dimorphic fungal infection capable of causing severe disseminated disease in immunocompromised hosts.

99.6-100%

Results

99.6-100%

sequence nearly matched the reference strain, confirming this fungal species

More results

Although traditionally endemic to North America, increasing molecular evidence suggests a broader geographic distribution.

We report a 31-year-old liver transplant recipient who developed progressive diffuse papulopustular and verrucous necrotic cutaneous lesions 17 months after transplantation.

More results

Definitive species identification was achieved by amplification and Sanger sequencing of the internal transcribed spacer (ITS1-5.8S-ITS2) region.

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Conclusion

This case highlights the diagnostic complexity of invasive fungal infections in non-endemic regions and emphasizes the importance of early molecular identification in immunocompromised patients presenting with atypical cutaneous and systemic fungal disease.

First Report of Fatal Disseminated Blastomyces percursus Infection in a Liver Transplant Recipient in Iran, a Non-endemic Country: A Case Report.

First Report of Fatal Disseminated Blastomyces percursus Infection in a Liver Transplant Recipient in Iran, a Non-endemic Country: A Case Report.

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