A Two-Stage Mohs Micrographic Surgery Technique to Avoid Complex Reconstruction of Large Skin Lesions.

Cohort studyLife (Basel, Switzerland)· Jun 2026

A Two-Stage Mohs Micrographic Surgery Technique to Avoid Complex Reconstruction of Large Skin Lesions.

Ariel Berl, Ofir Shir-Az, Biader Samih Bilal … Avshalom Shalom

Read paper

Dermatologic SurgeryCohort studyTreatmentQ1IF 4.3

Staged Mohs excision allowed primary closure for most large skin cancer defects

A Two-Stage Mohs Micrographic Surgery Technique to Avoid Complex Reconstruction of Large Skin Lesions.

Ariel Berl … Avshalom Shalom

Life (Basel, Switzerland) · Jun 2026

Background

Mohs Micrographic Surgery (Mohs Micrographic Surgery) is considered the most conservative and preserving procedure for removing cutaneous tumors.

Purpose

This retrospective cohort study describes our technique of serial Mohs excisions of large non-melanoma skin cancers for patients refusing flaps or skin graft reconstructions.

90%

Results

90%

primary closure worked for most large defects, avoiding complex reconstruction

n = 51 patients

More results

The major disadvantage of Mohs Micrographic Surgery is that tumor involvement in tissue may be underestimated.

This may lead to large excisions necessitating complex reconstruction with profound effects on cosmetic results.

The mean age was 76.5 (range 63-94) years and 55% were male.

Mean lesion sizes were 14.25-55 mm depending on location.

“

Conclusion

In conclusion, this approach of serial excisions with Mohs Micrographic Surgery can be performed safely and achieve better cosmetic outcomes for patients presenting with large skin tumors of the face or other functionally important areas.

A Two-Stage Mohs Micrographic Surgery Technique to Avoid Complex Reconstruction of Large Skin Lesions.

A Two-Stage Mohs Micrographic Surgery Technique to Avoid Complex Reconstruction of Large Skin Lesions.

Related papers