5-aminolevulinic acid-induced fluorescence-guided margin mapping and slow Mohs surgery for localized extramammary paget disease: A retrospective exploratory comparative study.

ALA-induced fluorescence-guided margin mapping may serve as a tissue-sparing adjunct within a pathology-driven surgical strategy for selected patients with localized Extramammary Paget disease.

In this exploratory cohort, it was associated with shorter treatment-process duration, smaller relative defects, lower reconstruction requirement, and higher exploratory patient-reported satisfaction.

These findings should not be interpreted as evidence of oncologic equivalence to slow Mohs surgery.