Case Report: Repigmentation and complete hair regrowth in an 11-year-old preadolescent with alopecia totalis…

Case reportFrontiers in pediatrics· 2026

Case Report: Repigmentation and complete hair regrowth in an 11-year-old preadolescent with alopecia totalis treated with a JAK inhibitor.

Yanhong Jia, Xue Wang, Yuanxiang Liu … Bin Zhang

Hair & NailCase reportTreatmentQ1IF 2.2

Case Report: Repigmentation and complete hair regrowth in an 11-year-old preadolescent with alopecia totalis treated with a JAK inhibitor.

Yanhong Jia … Bin Zhang

Frontiers in pediatrics · 2026

Background

Alopecia areata (areata) is an autoimmune disease characterized by non-scarring hair loss.

Results

hair fully regrew and repigmented, no residual bald or white patches

More results

An 11-year-old girl presented with alopecia totalis (alopecia totalis) persisting for two years.

She initially received baricitinib for seven months, achieving SALT 65% with predominantly white and gray hair regrowth.

The patient has now completed 12 months of ritlecitinib therapy with sustained response and stable pigmentation.

More results

Family Dermatology Life Quality Index (Family Dermatology Life Quality Index) decreased from 18 to 4.

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Conclusion

This case suggests that prolonged janus kinase inhibition may facilitate both hair regrowth and pigment restoration in pediatric severe areata.