Calcium Hydroxylapatite Combined with CO 2 Ablative Fractional Laser for Atrophic Acne Scars: A Randomized Controlled Study.
Adding calcium hydroxylapatite to laser sped healing of prolonged post-treatment redness.
Calcium Hydroxylapatite Combined with CO 2 Ablative Fractional Laser for Atrophic Acne Scars: A Randomized Controlled Study.
This study was to investigate the efficacy and safety of calcium hydroxylapatite (calcium hydroxylapatite) filler injections combined with CO 2 ablative fractional laser (ablative fractional laser) for atrophic acne scars.
A prospective, single-center, randomized controlled study was conducted on 160 participants, who were average randomly assigned to either an observation group (A) or a control group (B).
Compared with baseline, the quantitative global scarring grading system scores decreased significantly in both groups (p < 0.001), with greater reduction observed in group A (p < 0.001).
The acne scar rating scale analysis revealed the combination therapy's effectiveness across all scar subtypes (p < 0.001) and demonstrated comparable efficacy for boxcar and rolling scars (p = 1.000), both of which showed superiority to icepick scars (p < 0.001).
The combination of calcium hydroxylapatite with ablative fractional laser demonstrates both efficacy and safety for atrophic acne scars, particularly boxcar and rolling subtypes.
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