Epidermis to endocardium: mapping the association between atopic dermatitis and infective endocarditis.

This provides a biologically plausible bridge to infective endocarditis, which we explore in this current literature review.

Of the 16 studies, nine originated from Japan.

Mean age was 29.6 years (range 15-42 years), which is significantly younger than classic infective endocarditis cohorts (mean 60.0 years).

This potential link appears to be under-recognised, hence, greater cross-speciality awareness and rigorous atopic dermatitis control for those at high risk is recommended.