Clinical outcomes of atrial tachyarrhythmia hospitalizations with and without prior thoracic irradiation.

Cohort studyFrontiers in oncology· 2026

Clinical outcomes of atrial tachyarrhythmia hospitalizations with and without prior thoracic irradiation.

Aren Singh Saini, Sahil Ghay, Baneet Kaur … Crystal Seldon Taswell

Read paper

Hospital MedicineCohort studyPrognosisQ2IF 3.1

Prior thoracic irradiation linked to higher in-hospital mortality odds in atrial fibrillation or flutter admissions

Clinical outcomes of atrial tachyarrhythmia hospitalizations with and without prior thoracic irradiation.

Aren Singh Saini … Crystal Seldon Taswell

Frontiers in oncology · 2026

Background

Thoracic radiation therapy (thoracic radiation therapy) is commonly used for breast, lung, and lymphoid cancers.

Methods

A retrospective cohort study using the National Inpatient Sample (2016-2022) was conducted.

n = 3,198,304 weighted admissions

Results

prior chest radiation nearly doubled odds of dying in hospital

aOR 1.97 (95% CI 1.17 to 3.32)

CI excludes the null - significant

More results

Among 3,198,304 weighted admissions, 8,570 (0.27%) had prior thoracic radiation therapy.

“

Conclusion

DISCUSSION: Documented prior thoracic irradiation identified a clinically complex subgroup of atrial fibrillation or flutter hospitalizations with higher in-hospital mortality, slightly longer length of stay, and greater goals-of-care utilization.

Clinical outcomes of atrial tachyarrhythmia hospitalizations with and without prior thoracic irradiation.

Clinical outcomes of atrial tachyarrhythmia hospitalizations with and without prior thoracic irradiation.

Related papers