Association of Pitavastatin Versus Atorvastatin Therapy With Glycaemic Control and New-Onset Diabetes in…

Cohort studyBritish journal of hospital medicine (London, England : 2005)· Jul 2026

Association of Pitavastatin Versus Atorvastatin Therapy With Glycaemic Control and New-Onset Diabetes in Older Adults With Atherosclerotic Cardiovascular Disease.

Hongwen Li, Jie Li

Hospital MedicineCohort studyTreatmentQ3IF 1.3

Pitavastatin linked to lower odds of new-onset diabetes than atorvastatin in elderly patients

Association of Pitavastatin Versus Atorvastatin Therapy With Glycaemic Control and New-Onset Diabetes in Older Adults With Atherosclerotic Cardiovascular Disease.

Hongwen Li, Jie Li

British journal of hospital medicine (London, England · Jul 2026 · Q3 in General Medicine

Background

Statins are first-line therapy for atherosclerotic cardiovascular disease (atherosclerotic cardiovascular disease), but their differential effects on glucose metabolism, particularly in the elderly, remain a clinical concern.

Purpose

This study aimed to compare the effects of pitavastatin versus atorvastatin on glucose metabolism in elderly patients with atherosclerotic cardiovascular disease.

Methods

In this retrospective cohort study conducted at Public Health Clinical Center Affiliated to Shandong University between January 2022 and December 2023, 126 elderly atherosclerotic cardiovascular disease patients aged ≥60 years were included and allocated to either the pitavastatin group (4 mg/day, n = 58) or the atorvastatin group (20 mg/day, n = 68).

n = 58

OR 0.212

Results

OR 0.212

pitavastatin cut new-onset diabetes risk versus atorvastatin

n = 58

More results

No cases of new-onset diabetes were detected in the pitavastatin group, as compared to the 10.29% rate observed in the atorvastatin group.

“

Conclusion

Compared with atorvastatin, pitavastatin may be associated with better glycemic outcomes and a lower risk of new-onset diabetes in elderly atherosclerotic cardiovascular disease patients, supporting its consideration in clinical practice where glycemic control is a concern.

Association of Pitavastatin Versus Atorvastatin Therapy With Glycaemic Control and New-Onset Diabetes in Older Adults With Atherosclerotic Cardiovascular Disease.

Association of Pitavastatin Versus Atorvastatin Therapy With Glycaemic Control and New-Onset Diabetes in Older Adults With Atherosclerotic Cardiovascular Disease.

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