Pharmaceutical Interventions During Inpatient Care in a French Geriatric Hospital.
Prescribers accepted 65% of pharmacists' medication interventions in older inpatients.
Pharmaceutical Interventions During Inpatient Care in a French Geriatric Hospital.
Since aging is associated with pharmacokinetic and pharmacodynamic changes, polypharmacy is particularly harmful in older adults.
Therefore, this study aimed to characterize potential drug-related problems through the analysis of routine pharmaceutical interventions.
Data were collected from the electronic health record between 2019 and 2025; potentially inappropriate medications and high-risk medications were identified.
prescribers followed most pharmacist recommendations to adjust or stop medications
Among all pharmaceutical interventions, 1779 involved a potentially inappropriate medication.
The most frequent causes of drug-related problems were related to dose selection (39.8%), drug selection (14.3%), treatment duration (10.1%), and treatment safety (9.3%).
The most commonly targeted drug categories were the nervous system (24.7%), the digestive tract and metabolism (21.5%), blood and hematopoietic organs (19.8%), and the cardiovascular system (13.6%).
Pharmaceutical interventions that prevent prescribing errors in older adults are essential in clinical practice.
Understanding potential drug-related problems and the nature of pharmaceutical interventions can help ensure safe pharmacotherapy by alerting prescribers and caregivers to major medication-related risks.