A Wearable Extracorporeal Device for Imaging-Guided Therapy of Sepsis Through Rapid Removal of Bacteria.

Sepsis is a severe infectious disease triggered by pathogenic bacteria invading the bloodstream, with mortality risk increasing by 7%-9% for each hour of delayed treatment.

Real-time pathogen monitoring and rapid intervention are crucial for the timely and effective management of sepsis.

The polydimethylsiloxane microspheres exhibit excellent stability in the bloodstream and enable efficient bacterial removal by coupling with metabolic engineering.