Prediction of end-stage renal disease progression and mortality of advanced chronic kidney disease based on one year of serum albumin changes: a retrospective cohort study.

The predictor was the one-year percentage change in serum albumin (ΔAlbumin).

Outcomes included incident end-stage renal disease (end-stage renal disease) requiring dialysis, the composite of death and incident end-stage renal disease, and death before dialysis.

In restricted cubic spline models, a > 6.5% decrease in serum albumin was associated with a higher risk of dialysis, while a > 5.5% increase was associated with a lower risk.

In the marginal survival model, the results showed patients were more likely to receive dialysis before death (HR, 0.74; 95% CI, 0.65-0.84).