Differences and trends in pathogens between ventilator-associated pneumonia and non-ventilator-associated pneumonia: data from 61 hospitals in Suzhou, China, 2020-2024.
Drug-resistant bacteria more common in ventilator-associated than non-ventilator hospital pneumonia
Differences and trends in pathogens between ventilator-associated pneumonia and non-ventilator-associated pneumonia: data from 61 hospitals in Suzhou, China, 2020-2024.
To investigate the differences in pathogenic bacterial profiles between ventilator-associated pneumonia (ventilator-associated pneumonia) and non-ventilator-associated hospital-acquired pneumonia (NV-HAP) and to provide data to support clinical infection prevention and control.
Sixty-one secondary and tertiary healthcare institutions in a single city.
resistant strains more common in ventilator-linked pneumonia than non-ventilator cases
Pathogen distribution differed between the two groups, with Gram-negative bacteria being predominant in both groups (73.72% vs 80.98%).
Carbapenem-resistant Acinetobacter baumannii showed higher detection and composition ratios in the former group (77.37% and 48.05%, respectively).
The methicillin-resistant Staphylococcus aureus detection rates were approximately 50% in both groups, whereas the carbapenem-resistant Escherichia coli detection rate was below 6%.
S. maltophilia exhibited a ceftazidime resistance rate exceeding 36%, and B. cepacia exhibited ticarcillin/clavulanate and cefoperazone/sulbactam resistance rates exceeding 67%.
The two groups differed in the distribution and antimicrobial resistance of the pathogens and multidrug-resistant organisms, and these profiles fluctuated over time.
Patients with ventilator-associated pneumonia have a higher percentage of drug-resistant bacteria, requiring special attention to carbapenem-resistant Acinetobacter baumannii and carbapenem-resistant Pseudomonas aeruginosa.
Local microbiological epidemiological surveillance should be strengthened to improve infection prevention, control strategies and guide empirical antibiotic therapy.