Perioperative Discontinuation of Antiplatelet and Anticoagulation Therapy in Chronic Subdural Hematoma: Impact on in-Hospital Mortality, Functional Outcome, and Recurrence.

Prior anticoagulation therapy was discontinued at hospital admission and reinitiated 3 weeks postoperatively if chronic subdural hematoma resolution was complete.

Among 852 surgically treated chronic subdural hematoma patients (mean age 75.2 years; female-to-male ratio 1:2.1), univariate analysis revealed that prior anticoagulation therapy use was significantly associated with higher in-hospital mortality ( p = 0.043) and poor functional outcome ( p < 0.001), but not with recurrence ( p = 0.434).