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Cohort studyOman journal of ophthalmology · 2026

Role of concurrent intravenous pulse steroids and orbital radiation in the management of thyroid eye disease.

Nisar Sonam Poonam, Md Shahid Alam, Atanu Barh … Bipasha Mukherjee

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OphthalmologyCohort study

Combined IV steroids and orbital radiation resolved diplopia in most thyroid eye disease patients

Role of concurrent intravenous pulse steroids and orbital radiation in the management of thyroid eye disease.

Nisar Sonam Poonam … Bipasha Mukherjee

Oman journal of ophthalmology · 2026

Purpose

To analyze the outcomes of concurrent intravenous pulse steroids and orbital radiation (orbital radiation) in thyroid eye disease (thyroid eye disease).

Methods

It was a retrospective interventional study.

n = 24 patients

Results

diplopia (double vision) went away completely for most patients treated

Diplopia resolution

82.6%

Motility improvement

95.8%

More results

The mean age at presentation was 53.6 ± 11.4 years (range: 38-73 years).

The median duration of orbital disease was 5.5 months (range 1-96 months).

Diplopia (22, 91.66%) was the most common presenting complaint.

Posttreatment, there was a significant reduction in the mean inflammatory score ( P < 0.05).

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Conclusion · 1 of 2

Concurrent pulse intravenous methylprednisolone with orbital radiation is a safe and effective treatment modality for thyroid eye disease-related diplopia.

Conclusion · 2 of 2

An appropriate selection of cases along with a pretreatment magnetic resonance imaging to look for radiologically active disease aids in better planning and understanding of the disease.

Role of concurrent intravenous pulse steroids and orbital radiation in the management of thyroid eye disease.

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