OptiDON-Guard: An Ensemble Model for Identification of Dysthyroid Optic Neuropathy Using Optical Coherence Tomography Angiography.

The ensemble model, OptiDON-Guard, demonstrated superior performance to individual models on both internal validation and external test sets.

In the internal validation set, it achieved an AUC of 0.872, accuracy of 0.943, sensitivity of 0.667, specificity of 0.979, and precision of 0.943.