The Association Between Uveitis and Optic Neuritis in Central Nervous System Demyelinating Disorders: A Multi-Institutional Cohort Study.

The 5-year cumulative incidence of any uveitis among patients with optic neuritis in patients with multiple sclerosis was 0.986% (95% CI 0.846-1.15) compared to 0.543% (95% CI 0.437-0.676) in those without optic neuritis (log-rank P < 0.0001), with a HR of 1.95 (95% CI 1.51-2.53).

Intermediate uveitis demonstrated the strongest associations with optic neuritis across study groups.