Characteristics of Uveitis in European Tertiary Ophthalmology Centers: A Systematic Review and Meta-Analysis.

Meta-analysisOcular immunology and inflammation· May 2026

Characteristics of Uveitis in European Tertiary Ophthalmology Centers: A Systematic Review and Meta-Analysis.

Maja Cieślik, Maria Guszkowska, Bahram Bodaghi … Monika Łazicka-Gałecka

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UveitisMeta-analysisQ2IF 1.7

Anterior uveitis is the most common subtype in European tertiary centers.

Characteristics of Uveitis in European Tertiary Ophthalmology Centers: A Systematic Review and Meta-Analysis.

Maja Cieślik … Monika Łazicka-Gałecka

Ocular immunology and inflammation · May 2026 · Q2 in Ophthalmology

Background

Uveitis is one of the leading causes of preventable visual impairment and shows marked heterogeneity in anatomical distribution, etiology, and management.

Purpose

This systematic review and meta-analysis aims to contextualize characteristics of uveitis across European tertiary ophthalmology centers to provide a reference framework for clinical and research applications.

Methods

Observational cohort and cross-sectional studies including ≥ 50 adult uveitis patients managed in European tertiary referral centers were eligible.

n = 471 patients

Results

over half of patients had uveitis in the eye's front chamber

Anterior uveitis

52.1%

Posterior uveitis

18.9%

Panuveitis

14.4%

Intermediate uveitis

8.7%

More results

Etiologically, non-infectious uveitis predominated (44.9%, 95% CI: 39.4-50.5%), followed by idiopathic (34.3%, 95% CI: 29.9-39.0%) and infectious uveitis (23.0%, 95% CI: 20.6-25.5%).

All pooled estimates showed substantial heterogeneity (I 2 > 90%).

Treatment patterns and complication rates were inconsistently reported and are therefore summarized descriptively.

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Conclusion · 1 of 2

This study provides the first pooled benchmark estimates of uveitis characteristics across European tertiary centers, revealing substantial heterogeneity.

Conclusion · 2 of 2

The results offer a reference framework for contextualizing single-center cohorts and identifying regional variation across Europe.

Characteristics of Uveitis in European Tertiary Ophthalmology Centers: A Systematic Review and Meta-Analysis.

Characteristics of Uveitis in European Tertiary Ophthalmology Centers: A Systematic Review and Meta-Analysis.

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