Retinoblastoma research trends from 1980 to 2023: a 44-year bibliometric study.
United States led global retinoblastoma research output over 44 years, published 1662 papers.
Retinoblastoma research trends from 1980 to 2023: a 44-year bibliometric study.
Retinoblastoma (retinoblastoma) is the most common intraocular malignant tumor in children.
We extracted all retinoblastoma-related publications published from 1980 to 2023 from the Web of Science database and applied VOSviewer, R software, Bibliometrix software, Origin 2024 and CiteSpace to review the publication data, analyze the publication trends, and visualize the relevant data.
A total of 4156 papers on retinoblastoma were identified from 1980 to 2023.
In 1980, only 13 papers were published, yet by 2023, 237 papers had been published.
These publications were contributed by 351 research institutes from 68 countries/regions.
Thomas Jefferson University published the most research papers on retinoblastoma, with 166 published papers, accounting for 3.99% of all publications.
Over the past 44 years, the United States, China, India, Canada and Germany have led the field of research on retinoblastoma.
Many renowned research institutions and ophthalmologists have made important contributions to retinoblastoma research and will continue to lead this research direction.
Liquid biopsy, intra-arterial chemotherapy and intravitreal chemotherapy are potential hotspots for retinoblastoma research in the future.