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New research · Ophthalmology
BMC cancer · 15h
Systematic reviewBMC cancer · 2025

Pattern of Orbito-ocular Tumours in Nigeria: a systematic review.

Godswill I Nathaniel, Ugochukwu A Eze, Arinze A Onwuegbuna … Helen A Alen
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OphthalmologySystematic review

Nearly 60% of orbito-ocular tumours reported in Nigeria were malignant.

Pattern of Orbito-ocular Tumours in Nigeria: a systematic review.

Godswill I Nathaniel … Helen A Alen
BMC cancer · 2025
Background

Orbito-ocular tumours are stereotypical, monotonous growths of the orbit, eyeball, and extra-orbital tissues.

Purpose

To describe the patterns of these tumors in Nigeria.

Methods

A systematic literature search was conducted on Google Scholar and PubMed using the following keywords: pattern, orbit tumour, ocular tumour, Nigeria.

n = 2643 patients
nearly 60%
Results
nearly 60%
checks showed most reported tumours were cancerous rather than non-cancerous
n = 2643 patients
More results

A total of two thousand six hundred and forty-three (2643) patients with orbito-ocular tumors was reported to have been published in Nigerian articles over the past five decades, the age range of the reported cases was 1 month-93 years with a male preponderance.

Retinoblastoma and squamous cell carcinoma were the most common tumours in children and adults respectively.

More results

Squamous cell papilloma had the highest distribution among the benign category.

The eyeball and conjunctiva were the most common anatomical location of orbito-ocular tumors.

“
Conclusion · 1 of 3

There were more malignant than benign tumours from this review.

Conclusion · 2 of 3

The most common malignant tumours were retinoblastoma (in children) and conjunctival squamous cell carcinoma (in adults) while squamous papilloma was the most common benign tumour.

Conclusion · 3 of 3

Chemotherapy with or without surgeries was the most common intervention with varied treatment outcomes due to the nature and stage of tumour, adherence to treatment, and follow-up plan.

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