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New research · Ophthalmology
Journal of applied clinical medical physics · 15h
StudyJournal of applied clinical medical physics · 2025

Feasibility of treatment planning with HyperArc stereotactic radiosurgery methods for ocular tumors.

Chase Cochran, Shane McCarthy, William St Clair, Damodar Pokhrel
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OphthalmologyStudy

HyperArc stereotactic radiosurgery kept optic nerve dose significantly below the safety threshold.

Feasibility of treatment planning with HyperArc stereotactic radiosurgery methods for ocular tumors.

Chase Cochran … Damodar Pokhrel
Journal of applied clinical medical physics · 2025
Background

Various stereotactic radiosurgery (stereotactic radiosurgery) platforms have also been employed, yet widespread access remains a challenge.

Purpose

Currently, ocular disease is primarily managed with COMS plaque brachytherapy.

Methods

Twenty previously treated COMS patients with ocular melanoma were selected for a retrospective HyperArc stereotactic radiosurgery planning study.

Results

optic nerve radiation stayed well below the safety limit

HyTEC standard
12.1Gy
HyperArc optic nerve D
7.18Gy
More results

HyperArc plans demonstrated high conformality Paddick conformity index (PCI = 0.84 ± 0.04) with steep dose gradient index (GI = 3.29 ± 0.38).

Adequate planning target volumes coverage (D99% = 23.80 ± 0.46 Gy) was achieved with a mean gross tumor volume dose of 27.54 ± 0.47 Gy.

Average beam-on time was under 9 min.

More results

End-to-end quality assurance results showed a 99.00 ± 0.59% pass rate (2%/2 mm γ-criteria), with a Monte Carlo check showing 97.81 ± 1.24% agreement with the AcurosXB algorithm (2%/2 mm).

“
Conclusion · 1 of 2

HyperArc stereotactic radiosurgery plans provided adequate target coverage, acceptable organs at risk sparing, and offer a fast, safe, and non-invasive treatment option for ocular tumors.

Conclusion · 2 of 2

Clinical implementation of this novel methodology is ongoing at our institution.

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