Severe visual loss and ocular complications after intra-arterial chemotherapy for retinoblastoma.

Of the 71 eyes, 24 belonged to patients too immature for visual acuity assessment, and 20 were enucleated due to disease progression.

Among the 27 eyes with measurable visual acuity, 7 had a healthy fovea at diagnosis.

Only four eyes (14.8%) achieved a visual acuity<1.0 logMAR, all with a healthy fovea at diagnosis.

16 of 71 eyes (22.5%) developed choroidal occlusive vasculopathy, with statistically significant correlation with the number of intra-arterial chemotherapy cycles.