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Cohort studyJournal of epidemiology and global health · 2025

Indications for Pediatric Enucleations of Non-Retinoblastoma Globes in Saudi Arabia with Clinical and Radiological Correlation To Final Histopathological Diagnosis.

Azza My Maktabi, Hala A Helmi, Yaser M Benthabet … Hind Manaa Alkatan

OphthalmologyCohort study

Trauma-related causes account for over half of pediatric non-retinoblastoma enucleations.

Indications for Pediatric Enucleations of Non-Retinoblastoma Globes in Saudi Arabia with Clinical and Radiological Correlation To Final Histopathological Diagnosis.

Azza My Maktabi … Hind Manaa Alkatan

Journal of epidemiology and global health · 2025

Background

Enucleation is a difficult surgical decision in the ophthalmic practice.

Purpose

In this study we aim to investigate the indications -other than retinoblastoma- for enucleation in the pediatric age group to observe the trends and significant associations of these indications with our demographic and social background.

Methods

A retrospective cohort study of non-retinoblastoma globes based on histopathological examination obtained from pediatric patients younger than 18 years of age in a tertiary eye hospital over the period 2000 to 2021.

n = 47 patients

Results

57.4%

males slightly outnumbered females among children needing this surgery

n = 47 patients

More results

Ruptured globe was the main clinical indication in about half of the enucleations followed by painful blind or phthisical eyes.

Traumatic enucleations were significantly associated with older age group of 7 years or older (p = < 0.001).

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Conclusion · 1 of 3

Eye trauma is a leading cause for pediatric enucleation in about half of the non-retinoblastoma globes with higher prevalence in older children.

Conclusion · 2 of 3

When combined with end stage traumatized globes presenting as painful blind eye or phthisis bulbi, the rate increases to 57.4% of the enucleations.

Conclusion · 3 of 3

Health awareness and safety measures during sports and other activities should be implemented. Ophthalmologists should be aware of ophthalmic diseases presenting as pseudoretinoblastoma leading to possible unnecessary enucleations.

Post

Indications for Pediatric Enucleations of Non-Retinoblastoma Globes in Saudi Arabia with Clinical and Radiological Correlation To Final Histopathological Diagnosis.

Trauma-related causes account for over half of pediatric non-retinoblastoma enucleations.

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