Endoresection in Choroidal Melanoma: Outcomes of Intentional Incomplete Tumor Removal.

ObservationalCurrent oncology (Toronto, Ont.)· Dec 2025

Endoresection in Choroidal Melanoma: Outcomes of Intentional Incomplete Tumor Removal.

Alexander Anduaga-Beramendi, Marta Caminal-Caramés, Daniel Lorenzo … Josep M Caminal

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Ocular OncologyObservationalTreatmentQ2IF 3.6

Endoresection with intentional residual tumor gave 97% five-year survival in choroidal melanoma

Endoresection in Choroidal Melanoma: Outcomes of Intentional Incomplete Tumor Removal.

Alexander Anduaga-Beramendi … Josep M Caminal

Current oncology (Toronto, Ont.) · Dec 2025

Purpose

This technique aims to reduce surgical morbidity, while preserving visual function and maintaining effective local tumor control and survival.

Methods

We conducted a retrospective observational study including 33 patients with choroidal melanoma treated between January 2017 and August 2024 at a single tertiary ocular oncology center in Spain.

n = 33 patients

97%

Results

97%

checked survival after surgery - higher means more patients alive at 5 years

n = 33 patients

More results

Patients underwent pars plana vitrectomy and endoresection leaving residual tumor followed by ruthenium-106 brachytherapy.

Visual acuity of 20/200 or better was preserved in 60.61% of patients.

The most frequent complications were retinal detachment (36.36%) and macular edema (45.45%).

More results

Cytogenetic analysis showed a significant association between chromosome 1p loss and both recurrence and metastasis ( p = 0.032).

“

Conclusion

Further studies are required to validate its long-term efficacy.

Endoresection in Choroidal Melanoma: Outcomes of Intentional Incomplete Tumor Removal.

Endoresection in Choroidal Melanoma: Outcomes of Intentional Incomplete Tumor Removal.

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