Interferon Alpha-2a as Treatment for Primary Acquired Melanosis With Atypia and for Primary Acquired Melanosis With Atypia Surrounding Conjunctival Melanoma.

Topical interferon α-2a is safe and effective for treating primary acquired melanosis with atypia and for primary acquired melanosis with atypia surrounding conjunctival melanoma that arises from primary acquired melanosis with atypia, with high response rates and little to no toxicity.

Its similarity to interferon α-2b and safety profile make interferon α-2a a good alternative. Further large-scale, controlled studies are needed to validate these findings and their role in clinical practice.