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New research · Ophthalmology
Archivos de la Sociedad Espanola de Oftalmologia · 17h
Cross-sectionalArchivos de la Sociedad Espanola de Oftalmologia · 2026

Ocular neoplasms: Clinical, epidemiological, and histopathological analysis of mutilating procedures in a tertiary care hospital in Mexico.

C O Rojas-Arellanes, E de la Rosa-Jaime, X Monteon-Aspeitia … C Fuentes-Orozco
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OphthalmologyCross-sectional

Clinical and histopathological diagnoses agreed in most enucleated or exenterated ocular tumor cases.

Ocular neoplasms: Clinical, epidemiological, and histopathological analysis of mutilating procedures in a tertiary care hospital in Mexico.

C O Rojas-Arellanes … C Fuentes-Orozco
Archivos de la Sociedad Espanola de Oftalmologia · 2026
Background

Although uncommon, ocular neoplasms represent a significant cause of visual morbidity and, in some cases, mortality.

Purpose

The objective of this study was to analyze the epidemiological, clinical, and histopathological profile of patients who underwent enucleation or evisceration due to suspected ocular neoplasia at a tertiary care hospital in Mexico.

Methods

With suspected ocular neoplasms who underwent enucleation or exenteration were included.

n = 43 patients
90.7%
Results
90.7%
clinical exam and lab tissue diagnosis matched in nearly all cases
n = 43 patients
More results

The right eye was affected in 58.1% of cases.

The mean age was 2 ± 2 years in the pediatric group (n = 21) and 63.4 years in the adult group (n = 22).

The most frequent histopathological diagnosis was retinoblastoma (48.8%), followed by melanoma (23.3%) and squamous cell carcinoma (9.3%).

More results

The optic nerve was the most commonly infiltrated structure in retinoblastoma, while scleral infiltration predominated in melanoma.

“
Conclusion · 1 of 2

The age distribution and tumor types observed are consistent with those reported in the international literature. The high clinicopathological concordance highlights the importance of clinical judgment in managing these entities.

Conclusion · 2 of 2

Histopathological analysis is essential for prognostication and the development of early diagnostic strategies.

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