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New research · Ophthalmology
BMC infectious diseases · 23h
AI / informaticsBMC infectious diseases · 2026

Scaling trachoma surveillance in endemic areas using machine learning.

Benard W Kulohoma, Colette S A Wesonga
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OphthalmologyAI / informatics

Deep learning model identified trachoma from eyelid photos with 85% accuracy

Scaling trachoma surveillance in endemic areas using machine learning.

Benard W Kulohoma, Colette S A Wesonga
BMC infectious diseases · 2026
Background

Trachoma remains a leading infectious cause of blindness in endemic regions despite progress towards global elimination.

Methods

We retrospectively analysed anonymised inner eyelid photographs collected from trachoma prevalence surveys conducted in Ethiopia, Tanzania, Australia, Solomon Islands, Colombia, the Gambia, and Guatemala (n = 572 images).

n = 572 images
Results

correctly matched the expert diagnosis in most eyelid photos checked

80.9%
Sensitivity
90.5%
Specificity
More results

The model achieved a sensitivity of 80.9% for detecting trachoma and a specificity of 90.5% for correctly identifying non-trachoma eyes.

Agreement between predictions and grader labels was substantial (κ = 0.71, 95% CI 0.58–0.84).

“
Conclusion · 1 of 3

Our findings demonstrate the feasibility of using a reproducible R-based deep learning pipeline for automated trachoma classification in large-scale surveys.

Conclusion · 2 of 3

These findings demonstrate the feasibility of automated trachoma classification using a transfer-learning framework. Larger datasets will be required before operational deployment in surveillance programmes.

Conclusion · 3 of 3

CLINICAL TRIAL NUMBER: Not applicable.

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