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Cohort studyEuropean journal of ophthalmology · 2026

Correlation of visual function with semi-quantitative MRI findings in cerebral visual impairment.

Esma Yüzügüldü, Hande Taylan Şekeroğlu, Ata Baytaroğlu … Rahşan Göçmen

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OphthalmologyCohort study

MRI brain damage severity strongly correlates with visual acuity in cerebral visual impairment

Correlation of visual function with semi-quantitative MRI findings in cerebral visual impairment.

Esma Yüzügüldü … Rahşan Göçmen

European journal of ophthalmology · 2026

Purpose

To evaluate visual function in children with cerebral visual impairment (cerebral visual impairment) from various causes, examine its relationship with the severity of cerebral involvement using a semi-quantitative MRI scoring system (sqMRI), and compare the results with strabismic controls without visual impairment.

Methods

This retrospective study included children diagnosed with cerebral visual impairment and controls without cerebral visual impairment who were followed for strabismus.

n = Forty-two children with CVI and 40

partial r = 0.78

Results

partial r = 0.78

worse brain scan damage strongly predicts worse eyesight

n = Forty-two children with CVI and 40

More results

Hypoxic-ischemic encephalopathy was the most common cause (26.1%).

Children with cerebral visual impairment had significantly lower gestational ages, birth weights, and best-corrected visual acuity (BCVA) (mean 0.28 ± 0.17 logMAR) compared to controls (0.05 ± 0.05 logMAR) (p < 0.001).

More results

The sqMRI scores showed significant correlation with BCVA, especially in the basal ganglia, thalamus, hemispheric, subcortical, and total MRI scores ( p < 0.05).

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Conclusion · 1 of 2

A strong, prematurity-independent correlation was observed between sqMRI scores and visual impairment in a clinically diverse cerebral visual impairment population.

Conclusion · 2 of 2

These findings suggest that sqMRI scoring could be a useful additional tool for visual prognosis and early rehabilitation planning.

Post

Correlation of visual function with semi-quantitative MRI findings in cerebral visual impairment.

MRI brain damage severity strongly correlates with visual acuity in cerebral visual impairment

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