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New research · Ophthalmology
Ophthalmology · 1d
Cohort studyOphthalmology · 2026

Prevalence of Strabismus and Decreased Stereopsis in Parents of Children with Strabismus.

Sarah MacKinnon, Rachael Zacks, Brenda Barry … Strabismus Genetics Research Consortium
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OphthalmologyCohort study

Most fathers of children with strabismus have abnormal eye alignment or vision test results.

Prevalence of Strabismus and Decreased Stereopsis in Parents of Children with Strabismus.

Sarah MacKinnon … Strabismus Genetics Research Consortium
Ophthalmology · 2026
Purpose

This study investigates the prevalence of strabismus and subnormal stereopsis in parents of children with various types of strabismus, including infantile, accommodative, nonaccommodative esotropia, and exotropia.

Methods

A total of 2164 parents of children with strabismus were enrolled; 481 (303 mothers and 178 fathers) underwent orthoptic examination.

n = 208 control
Results

most fathers had abnormal eye alignment or vision test results

Mothers
50.2%
Fathers
60.1%
More results

Specifically, 22.4% of mothers and 28.1% of fathers were diagnosed with strabismus, and 27.7% of mothers and 32.0% of fathers had conditions associated with strabismus (subnormal stereopsis, phorias 10 prism diopters (prism diopters) or more, or a history of patching and exercises).

More results

There were no significant differences in rates of abnormal parental examination results based on strabismus type of the child.

Most parents shared the same deviation type with their children, signifying familial phenotypic inheritance.

Stereopsis was subnormal in 14.9% of controls.

“
Conclusion · 1 of 3

This study highlights the familial nature of strabismus and high rate of abnormal stereopsis in parents of children with strabismus. This suggests that low stereopsis may be a subclinical form of strabismus.

Conclusion · 2 of 3

A notable discrepancy in self-reported and examined diagnoses underscores the need for clinical evaluations.

Conclusion · 3 of 3

Our findings suggest that low stereopsis could be used as a phenotype in large biobank genetic studies to allow greater understanding of strabismus, which is often neglected in eye genetic studies.

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