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New research · Ophthalmology
In vivo (Athens, Greece) · 1d
Case reportIn vivo (Athens, Greece) · 2026

Management of a Complex Orbital Post-transplantation Lymphoproliferative Disorder: A Case Report and Literature Review.

Tessho Maruyama, Yohei Hokama, Kazutaka Kishaba … Tadashi Hamasaki
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OphthalmologyCase report

Localized orbital lymphoproliferative disorder remained in remission after immunosuppression reduction alone.

Management of a Complex Orbital Post-transplantation Lymphoproliferative Disorder: A Case Report and Literature Review.

Tessho Maruyama … Tadashi Hamasaki
In vivo (Athens, Greece) · 2026
Background

Post-transplantation lymphoproliferative disorder (post-transplantation lymphoproliferative disorder) is an uncommon but serious complication of organ transplantation.

13
Results
13
months
immunosuppression alone kept the eye lesion controlled, no relapse, over a year
More results

Management often requires multiple treatment modalities and reduction in immunosuppressant treatment (reduction in immunosuppressant treatment).

Orbital involvement is rare, and optimal diagnostic and therapeutic approaches remain uncertain.

More results

CASE REPORT: Here, we report a case of localized orbital post-transplantation lymphoproliferative disorder that was successfully treated with reduction in immunosuppressant treatment alone.

A 62-year-old man, who had undergone kidney transplantation 18 years prior, presented with left eye pain and proptosis.

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Conclusion

This case suggests the potential role of a conservative, individualized, stepwise approach in selected patients with localized orbital post-transplantation lymphoproliferative disorder, and may inform management strategies for other localized forms of post-transplantation lymphoproliferative disorder.

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