Prevalence of intraretinal and subretinal fluid in acute non-arteritic anterior ischemic optic neuropathy.
Peripapillary fluid buildup occurs in nearly half of acute optic nerve stroke cases.
Prevalence of intraretinal and subretinal fluid in acute non-arteritic anterior ischemic optic neuropathy.
This cross-sectional study aimed to characterise the prevalence and severity of intraretinal (IRF) and subretinal fluid (subretinal fluid) in in non-arteritic ischemic optic neuropathy (non-arteritic ischemic optic neuropathy).
Two neuro-ophthalmologists assessed optical coherence tomography scans of patients diagnosed with acute non-arteritic ischemic optic neuropathy at a tertiary neuro-ophthalmology centre between July 2022 and July 2024 for peripapillary subretinal fluid, peripapillary IRF, and foveal subretinal fluid.
affected nearly half of patients, showing fluid buildup around the optic nerve is common
Peripapillary subretinal fluid did not extend beyond a quarter of the distance from the disc margin to the fovea, but peripapillary IRF extended more than halfway in 9 (28.1%) cases.
Compared to patients without peripapillary IRF, patients with peripapillary IRF had a greater baseline RNFL thickness (P = 0.02) and smaller CDRs in the unaffected eye (average CDR, P = 0.002).
Peripapillary IRF restricted to the peripapillary region occurs in one-third of acute non-arteritic ischemic optic neuropathy cases but peripapillary IRF extending more than 50% to the fovea, peripapillary subretinal fluid, and foveal subretinal fluid are uncommon.
Patients with smaller optic discs and more severe disc oedema may be more likely to develop peripapillary IRF and foveal subretinal fluid.