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New research · Ophthalmology
The Journal of craniofacial surgery · 1d
Cohort studyThe Journal of craniofacial surgery · 2026

The Visual Function of Emergent Transnasal Endoscopic Orbital Decompression Surgery for Patients With Steroid-Resistant Dysthyroid Optic Neuropathy.

Cheng Xiong, Yangming Ou, Dan Wen … Wei Chi
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OphthalmologyCohort study

Emergent decompression surgery was linked to vision improvement in most steroid-resistant optic neuropathy patients

The Visual Function of Emergent Transnasal Endoscopic Orbital Decompression Surgery for Patients With Steroid-Resistant Dysthyroid Optic Neuropathy.

Cheng Xiong … Wei Chi
The Journal of craniofacial surgery · 2026
Background

Dysthyroid optic neuropathy (dysthyroid optic neuropathy) is occasionally resistant to corticosteroid treatment.

Methods

Thirteen patients with steroid-resistant dysthyroid optic neuropathy seen at Shenzhen Eye Hospital (China) between January 2023 and April 2025 were included in our study.

n = 13 patients
Results

surgery restored vision in most patients when done early

Preoperative
0.76LogMAR
Postoperative
0.23LogMAR
More results

The duration of dysthyroid optic neuropathy ranged from 9 to 36 months (median time 17.4 mo).

These 11 patients underwent decompression within <26 months of diagnosis.

Three of these 11 patients demonstrated pronounced BCVA improvement: 2 of them improved from counting fingers to 0.6 and 0.02, respectively, and the other improved from hand motion to 0.3.

More results

However, the remaining 2 showed no improvement.

“
Conclusion · 1 of 2

Emergent transnasal endoscopic orbital decompression surgery is a very useful and effective treatment for dysthyroid optic neuropathy (dysthyroid optic neuropathy) that is refractory to corticosteroid therapy.

Conclusion · 2 of 2

Its efficacy seems inversely correlated with disease duration rather than preoperative BCVA. As such, longer disease duration may be associated with poorer postoperative outcomes.

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