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New research · Ophthalmology
Frontiers in neurology · 1d
AI / informaticsFrontiers in neurology · 2026

A CT radiomics nomogram predicts visual acuity improvement in patients with indirect traumatic optic neuropathy following optic canal decompression.

Guangyu Wang, Pengran Yu, Shuo Li, Wenchuan Zhang
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OphthalmologyAI / informatics

A CT-based nomogram identifies which patients regain vision after optic nerve decompression surgery.

A CT radiomics nomogram predicts visual acuity improvement in patients with indirect traumatic optic neuropathy following optic canal decompression.

Guangyu Wang … Wenchuan Zhang
Frontiers in neurology · 2026
Background

Indirect traumatic optic neuropathy (indirect traumatic optic neuropathy) is a common cause of persistent visual impairment following craniofacial trauma.

Methods

Were randomly assigned to training ( n = 118) and test ( n = 51) sets in a 7:3 ratio.

n = 169 patients
Results

low-risk patients regained vision far more often than high-risk patients

Low-risk (training)
87.9%
High-risk (training)
30.5%
More results

The final nomogram incorporated nine radiomics features and three clinical predictors.

It demonstrated robust discriminative ability, with area under the curve values of 0.840 in the training set and 0.832 in the test set.

This tool effectively categorized patients into distinct risk groups for poor visual acuity recovery.

“
Conclusion

The developed clinical-radiomics nomogram represents a valuable non-invasive tool for the preoperative prediction of visual acuity improvement following optic canal decompression in patients with indirect traumatic optic neuropathy, showing significant potential to inform personalized treatment strategies.

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