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New research · Ophthalmology
Canadian journal of ophthalmology. Journal canadien d'ophtalmologie · 1d
StudyCanadian journal of ophthalmology. Journal canadien d'ophtalmologie · 2026

Concurrent validity estimates for the accuracy of administrative data case definitions for uveitis in Ontario, Canada.

Tina Felfeli, Laura Rosella, Sherif El-Defrawy … Jessica Widdifield
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OphthalmologyStudy

At least one uveitis diagnosis code best detects true uveitis cases in health records.

Concurrent validity estimates for the accuracy of administrative data case definitions for uveitis in Ontario, Canada.

Tina Felfeli … Jessica Widdifield
Canadian journal of ophthalmology. Journal canadien d'ophtalmologie · 2026
Purpose

This study aimed to validate administrative data case definitions for identifying individuals with uveitis within health administrative data and to assess case definition performance in different age groups.

Methods

Among 200,386 eligible patients in a large, province-wide, multisite primary care electronic medical record data repository in Ontario, Canada, 1 020 individuals were selected for medical review based on uveitis-related search terms.

n = 431 cases
Results

diagnosis codes correctly flagged about 3 in 4 true uveitis cases

Sensitivity 74 (95% CI 69.90 to 78.20)
null = 069.9078.20
CI excludes the null - significant
More results

Within the validation sample, the median age of identified uveitis patients was 55 years, with the majority falling within the 26-64 age group.

Females represented 59.9% of cases.

Family physicians (72.2%) and ophthalmologists (60.6%) were the most common sources of diagnosis documentation, and anterior uveitis was the most prevalent classification (64.0%).

More results

PPV increased with more physician diagnosis codes but was accompanied by decreased sensitivity.

“
Conclusion

This study identified administrative data case definitions for identifying uveitis, with varying sensitivity and PPV for a range of research purposes and data availability.

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