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New research · Ophthalmology
Cureus · 1d
Case reportCureus · 2026

Endogenous Methicillin-Resistant Staphylococcus aureus (MRSA) Endophthalmitis Presenting as an Anterior Chamber Abscess With Necrotizing Scleritis.

Zach P Dawson, Alec Curtis, Stephen Cross, Adam Pearlman
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OphthalmologyCase report

In this case, vision recovered from light perception to 20/30 after targeted treatment.

Endogenous Methicillin-Resistant Staphylococcus aureus (MRSA) Endophthalmitis Presenting as an Anterior Chamber Abscess With Necrotizing Scleritis.

Zach P Dawson … Adam Pearlman
Cureus · 2026
Background

To report a rare presentation of endogenous methicillin-resistant Staphylococcus aureus (methicillin-resistant Staphylococcus aureus) endophthalmitis with necrotizing scleritis manifesting as an anterior chamber (anterior chamber) abscess, and to highlight the diagnostic value of repeating anterior chamber sampling when clinical suspicion for infection remains high.

20/30
Results
20/30
Eyesight went from barely detecting light to near-normal (20/30) vision in this one patient.
More results

A 29-year-old man developed a progressive anterior chamber mass and decreased vision one week after incision and drainage of an methicillin-resistant Staphylococcus aureus thigh abscess.

Ocular symptoms progressed for two months before ophthalmic evaluation revealed a large anterior chamber lesion with hypopyon and early scleral thinning.

More results

An initial anterior chamber tap was negative; corticosteroids were associated with clinical worsening.

A repeat anterior chamber tap demonstrated Gram-positive cocci , and cultures confirmed methicillin-resistant Staphylococcus aureus.

“
Conclusion

Early targeted intravitreal antibiotics and coordinated subspecialty care can preserve vision.

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