The Effects of a Digital Mindfulness Intervention on Mental Health and Vision-Related Quality of Life in Noninfectious Uveitis.
Digital mindfulness app reduced anxiety symptoms in adults with uveitis.
The Effects of a Digital Mindfulness Intervention on Mental Health and Vision-Related Quality of Life in Noninfectious Uveitis.
To evaluate the effect of a digital mindfulness-based program (Calm Health) on mental health outcomes in adults with noninfectious uveitis (noninfectious uveitis).
One hundred adults aged ≥18 years with active or inactive noninfectious uveitis and baseline mild or greater anxiety or depression were randomized 1:1 to immediate access to a mindfulness application (app) (Calm Health) or to a waitlist control group.
less anxiety on a standard symptom checklist after using the app
Of 100 randomized participants (median age 43.5 years; 75% female), 70 completed the primary endpoint assessment.
Median [Q1, Q3] total app use among intervention participants was 578.62 [397.79, 923.00] minutes over 8 weeks.
Secondary analyses showed significantly greater reductions in PHQ-9 scores (-1.90 points; 95% CI, -3.04 to -0.76, P = 0.001) and PSS-10 scores (-3.69 points; 95% CI, -6.00 to -1.37, P = 0.002) in the intervention group.
Changes in NEI VFQ-25 scores were not statistically significant between groups (mean difference 1.98 points; 95% CI, -0.90 to 4.86, P = 0.18).
A digital mindfulness-based intervention (Calm Health) significantly reduced anxiety, depression, and perceived stress in adults with noninfectious uveitis.
Digital mindfulness tools may serve as a feasible, scalable adjunct to uveitis care, particularly in settings with limited access to traditional mental health services.
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