Secondary extraocular extension of choroidal melanoma following primary photodynamic therapy.
Secondary extraocular tumor spread is a rare but real risk after photodynamic therapy for choroidal melanoma.
Secondary extraocular extension of choroidal melanoma following primary photodynamic therapy.
Secondary extraocular extension (secondary extraocular extension) following conservative treatment of choroidal melanoma (choroidal melanoma) is extremely rare, and its occurrence in patients treated with primary photodynamic therapy (photodynamic therapy) has not been documented in the literature so far.
Retrospective, observational case series.
All patients were treated with photodynamic therapy after extensive counselling of all treatment options.
All displayed local tumour control following initial treatment.
Secondary extraocular extension occurred at a mean of 42.3 months [range 24-66] after treatment.
Secondary extraocular extension was identified following enucleation for suspected intraocular clinical recurrence, or on surveillance ocular imaging (US and MRI).
Local radiotherapy remains the mainstay of treatment for small choroidal melanoma due to its superior local tumour control rates.
Prior to this study, there had been no reports of secondary extraocular extension following photodynamic therapy for choroidal melanoma, so surveillance for recurrence was not designed to detect this complication.
This series establishes that secondary extraocular extension is a rare but important potential risk following photodynamic therapy, and patients should be both counselled of this, and monitored for it.