Health-related quality of life and visual function in retinoblastoma survivors with ocular prostheses: a…

Cross-sectionalScientific reports· May 2026

Health-related quality of life and visual function in retinoblastoma survivors with ocular prostheses: a cross-sectional study.

Beatrice Casslén, Richard Jonasson, Marie Odersjö … Marita Andersson Grönlund

Ocular OncologyCross-sectionalClinical practiceQ1IF 5.0

Retinoblastoma survivors with subnormal vision report much lower quality of life

Health-related quality of life and visual function in retinoblastoma survivors with ocular prostheses: a cross-sectional study.

Beatrice Casslén … Marita Andersson Grönlund

Scientific reports · May 2026

Background

Retinoblastoma (retinoblastoma) survivors who have undergone enucleation and use ocular prostheses may face long-term challenges related to visual function and overall well-being.

Purpose

This study aimed to evaluate health-related quality of life (health-related quality of life) and visual function in this population, addressing a gap in knowledge regarding their lived experiences and functional vision.

Methods

This cross-sectional study included 12 unilateral and 3 bilateral retinoblastoma survivors (10 girls, 5 boys; mean age 15.5 years, range 6.8-26.5), all treated with unilaterally enucleation and an ocular prosthesis at Sahlgrenska University Hospital, Sweden (2000-2019).

Results

with blurry or reduced vision, survivors rated their life quality much worse

64.1PedsQL

Subnormal BCVA

88PedsQL

Normal BCVA

More results

Results were compared with age-matched healthy controls.

Self-reported PedsQL total score (82.5) equalled normative data (83.0) and parents' report (82.5).

The number of affected perceptual visual dysfunctions areas correlated with age (r = 0.59, p = 0.022), but not with BCVA or PedsQL score.

“

Conclusion

Retinoblastoma survivors with ocular prostheses require holistic care that includes assessment of health-related quality of life and functional vision, beyond visual acuity, to identify unmet needs and guide interventions that support overall well-being and optimal long-term outcomes.

Health-related quality of life and visual function in retinoblastoma survivors with ocular prostheses: a cross-sectional study.

Health-related quality of life and visual function in retinoblastoma survivors with ocular prostheses: a cross-sectional study.

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