Unilateral Glaucoma as a Clinical Indicator of Iris and Ciliary Body Melanoma.

Unilateral glaucoma is significantly more common in eyes with iris and ciliary body melanoma than in those with iris and ciliary body nevus in this claims-based cohort, and melanoma patients are more likely to require surgical management.

Unilateral glaucoma may serve as an important early clinical indicator of melanoma, although further clinical correlation is necessary.

Incorporating glaucoma status into diagnostic criteria could improve recognition, prompt referral and biopsy, and reduce delays in treatment.