DOTATATE PET scan detects meningiomas more accurately than Magnetic Resonance Imaging
Role of DOTATATE PET Imaging in Meningiomas with Neuro-Ophthalmic Implications.
Samir Touma … Katie Luneau
Neuro-ophthalmology (Aeolus Press) · 2026
Background
Meningiomas are the most frequent primary intracranial tumors.
Purpose
This literature review aims to evaluate the role of 68 Gallium DOTATATE PET scan in the diagnosis and management of meningiomas, specifically optic nerve sheath meningiomas (optic nerve sheath meningiomas).
Results
PET scan spotted meningioma tissue more reliably than Magnetic Resonance Imaging in these studies
68Ga-DOTATATE PET sens
90.1%
MRI sensitivity
79%
More results
Neuroimaging remains a pillar for the diagnosis and the clinical decisions that follow.
Magnetic Resonance Imaging (Magnetic Resonance Imaging) has been the gold standard tool for evaluating meningiomas, alongside CT scans.
More results
However, many obstacles persist, hence the need for new technologies providing functional and molecular information on these tumors.
The addition of 68 Ga-DOTATATE to the clinical management of meningiomas with neuro-ophthalmic implications turned out to be beneficial for the diagnosis, surgical planning, post-surgical radiation, and surveillance.
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Conclusion
This technology could allow to overcome certain limitations found with MRIs and CT scans, such as delineating tumor spread in anatomically challenging areas as well as attributing smaller and more precise radiation volumes.