Post

New research · Ophthalmology
Investigative ophthalmology & visual science · 2d
StudyInvestigative ophthalmology & visual science · 2026

Exogenous Fusarium Endophthalmitis: Clinical Features, Treatment Modalities, and Visual Outcomes.

Sujin Kang, William E Smiddy, Nicolas A Yannuzzi … Harry W Flynn
Read paper
OphthalmologyStudy

Only 29% achieved decent vision after treatment for Fusarium eye infection.

Exogenous Fusarium Endophthalmitis: Clinical Features, Treatment Modalities, and Visual Outcomes.

Sujin Kang … Harry W Flynn
Investigative ophthalmology & visual science · 2026
Purpose

To characterize the clinical features, treatment modalities, and visual outcomes of culture-proven exogenous Fusarium endophthalmitis managed at a tertiary referral center.

Methods

This retrospective, single-center, consecutive case series included 14 eyes of 14 patients with culture-proven exogenous Fusarium endophthalmitis treated between October 2014 and December 2025.

n = 14 eyes
29%
Results
29%
less than a third of patients regained functional, usable eyesight
n = 14 eyes
More results

Median presenting best-corrected visual acuity (BCVA) was 2.40 logMAR (∼20/5000).

Infection sources included trauma (7/14, 50%), anterior segment surgery (5/14, 36%), and contact lens-associated fungal keratitis (2/14, 14%).

More results

All eyes required combined antifungal therapy (topical, intravitreal, intracameral, and/or intrastromal with systemic treatment) and surgical intervention, including therapeutic penetrating keratoplasty (14/14, 100%) and vitrectomy (8/14, 57%).

“
Conclusion · 1 of 2

Exogenous Fusarium endophthalmitis is a serious ocular infection requiring multimodal therapy and multiple surgical interventions, yet long-term visual outcomes remain poor.

Conclusion · 2 of 2

Early fungal recognition and prompt antifungal treatment may improve outcome.

Read paper
0 comments

No comments yet. Be the first.

Related papers

LatestFoundational
Cross-sectional
44.1%
had too much homocysteine in the blood, a far larger share than in dry AMD or healthy eyes
Cohort Study
92.3%
most laser-treated eyes had a favorable eye-structure outcome
Cohort Study
56%
lost three or more lines on the eye-chart vision test
Cohort Study
50%
older patients were more likely to lose three or more lines of vision
Study
81%
trials where mask air leaks were detected blowing toward the eyes
Cohort Study
13.5%
Central retinal artery peak blood-flow speed was 13.5% lower in diabetic patients.
Study
379 +/- 156 microm
lower thickness in the central retina, checked with an eye scan
Case Report
9 of 10 eyes
eyes had better measured vision after treatment