Reproducibility of Perfusion-Weighted and Diffusion-Weighted Magnetic Resonance Imaging in Patients with…

StudyOcular oncology and pathology· Jun 2026

Reproducibility of Perfusion-Weighted and Diffusion-Weighted Magnetic Resonance Imaging in Patients with Ocular Tumours.

Pieter A M Janssen, Teresa A Ferreira, T H Khanh Vu … Lisa Klaassen

Ocular OncologyStudyDiagnosisQ2IF 1.7

Diffusion MRI measurements of eye tumors are highly reproducible across two imaging centers.

Reproducibility of Perfusion-Weighted and Diffusion-Weighted Magnetic Resonance Imaging in Patients with Ocular Tumours.

Pieter A M Janssen … Lisa Klaassen

Ocular oncology and pathology · Jun 2026

Background

Diffusion-weighted imaging (diffusion-weighted imaging) and perfusion-weighted imaging (perfusion-weighted imaging) can assess biological tumour characteristics of uveal melanoma (uveal melanoma), the most common primary intraocular malignant tumour in adults.

Purpose

Therefore, this study aimed to assess the reproducibility of ocular diffusion-weighted imaging and perfusion-weighted imaging measurements between two centres.

Methods

In this prospective study, 15 patients with uveal melanoma were included.

n = 15 patients

Results

difference between the two hospitals' scans was tiny - showing very high consistency

MD 0.07 (95% CI 0.04 to 0.11)

null 0

0.04

0.11

CI excludes the null - significant

“

Conclusion

This study shows that diffusion-weighted imaging and perfusion-weighted imaging parameters demonstrate reproducibility in uveal melanoma patients between two different centres, with variabilities smaller than differences typically observed in differential diagnosis or treatment response assessments.

Reproducibility of Perfusion-Weighted and Diffusion-Weighted Magnetic Resonance Imaging in Patients with Ocular Tumours.

Reproducibility of Perfusion-Weighted and Diffusion-Weighted Magnetic Resonance Imaging in Patients with Ocular Tumours.

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