Post

New research · Ophthalmology
Ocular oncology and pathology · 2d
StudyOcular oncology and pathology · 2026

Reproducibility of Perfusion-Weighted and Diffusion-Weighted Magnetic Resonance Imaging in Patients with Ocular Tumours.

Pieter A M Janssen, Teresa A Ferreira, T H Khanh Vu … Lisa Klaassen
Read paper
OphthalmologyStudy

Diffusion MRI measurements of eye tumors are highly reproducible across two imaging centers.

Reproducibility of Perfusion-Weighted and Diffusion-Weighted Magnetic Resonance Imaging in Patients with Ocular Tumours.

Pieter A M Janssen … Lisa Klaassen
Ocular oncology and pathology · 2026
Background

Diffusion-weighted imaging (diffusion-weighted imaging) and perfusion-weighted imaging (perfusion-weighted imaging) can assess biological tumour characteristics of uveal melanoma (uveal melanoma), the most common primary intraocular malignant tumour in adults.

Purpose

Therefore, this study aimed to assess the reproducibility of ocular diffusion-weighted imaging and perfusion-weighted imaging measurements between two centres.

Methods

In this prospective study, 15 patients with uveal melanoma were included.

n = 15 patients
Results

difference between the two hospitals' scans was tiny - showing very high consistency

MD 0.07 (95% CI 0.04 to 0.11)
null 0
0.04
0.11
CI excludes the null - significant
“
Conclusion

This study shows that diffusion-weighted imaging and perfusion-weighted imaging parameters demonstrate reproducibility in uveal melanoma patients between two different centres, with variabilities smaller than differences typically observed in differential diagnosis or treatment response assessments.

Read paper
0 comments

No comments yet. Be the first.

Related papers

LatestFoundational
Cross-sectional
44.1%
had too much homocysteine in the blood, a far larger share than in dry AMD or healthy eyes
Cohort Study
92.3%
most laser-treated eyes had a favorable eye-structure outcome
Cohort Study
56%
lost three or more lines on the eye-chart vision test
Cohort Study
50%
older patients were more likely to lose three or more lines of vision
Study
81%
trials where mask air leaks were detected blowing toward the eyes
Cohort Study
13.5%
Central retinal artery peak blood-flow speed was 13.5% lower in diabetic patients.
Study
379 +/- 156 microm
lower thickness in the central retina, checked with an eye scan
Case Report
9 of 10 eyes
eyes had better measured vision after treatment