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Case reportJournal of current ophthalmology · 2025

Twelve-Month Visual and Anatomical Outcomes of Boston Type I Keratoprosthesis in Four Patients with Multiple Graft Failures and Severe Ocular Pathology.

Hamed Ghasemi, Pirouzeh Farsi, Amirsadra Zangouei, Hassan Hashemi

OphthalmologyCase report

All eyes achieved functional vision (20/200 or better) by 6 months after keratoprosthesis.

Twelve-Month Visual and Anatomical Outcomes of Boston Type I Keratoprosthesis in Four Patients with Multiple Graft Failures and Severe Ocular Pathology.

Hamed Ghasemi … Hassan Hashemi

Journal of current ophthalmology · 2025

Purpose

To assess 12-month visual acuity, anatomic integrity, and complication rates after Boston Type I Keratoprosthesis (BKPro-I) implantation in eyes with multiple failed penetrating keratoplasties and complex anterior segment pathology.

Methods

In this prospective case series, four eyes (mean age, 32 ± 9 years) received BKPro-I between January and June 2022.

Results

100%

Every one of the 4 eyes reached vision of 20/200 or better within 6 months of the artificial cornea implant.

More results

At 12 months, all devices were retained.

Two eyes (50%) developed complications - retroprosthetic membranes, vitritis/suspected endophthalmitis, stromal melting, chronic hypotony, and silicone-oil leak - all managed without device loss; one eye's vision declined to finger counting at month 7 but remained ambulatory.

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Conclusion · 1 of 2

BKPro-I yields excellent short-term visual rehabilitation and perfect retention in highly complex eyes.

Conclusion · 2 of 2

However, a 50% complication rate mandates rigorous patient selection, standardized perioperative protocols, and lifelong multidisciplinary follow-up.

Post

Twelve-Month Visual and Anatomical Outcomes of Boston Type I Keratoprosthesis in Four Patients with Multiple Graft Failures and Severe Ocular Pathology.

All eyes achieved functional vision (20/200 or better) by 6 months after keratoprosthesis.

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