Post

New research · Ophthalmology
PeerJ · 2d
Systematic reviewPeerJ · 2026

Effectiveness of treatment approaches for childhood exotropia: a systematic review.

Saif Hassan Alrasheed, Saleh Alshammeri
Read paper
OphthalmologySystematic review

Part-time occlusion plus OBVAT had the highest short-term success in childhood exotropia treatment

Effectiveness of treatment approaches for childhood exotropia: a systematic review.

Saif Hassan Alrasheed, Saleh Alshammeri
PeerJ · 2026
Background

Exotropia (XT), an outward ocular deviation, commonly affects children.

Purpose

The aim of this systematic review is to evaluate the evidence on the effectiveness, indications, and clinical outcomes of different treatment modalities for childhood XT.

Methods

The review protocol was registered in the International Prospective Register of Systematic Reviews (PROSPERO) under registration number CRD420251174532.

n = 3,643 children
86.8%
Results
86.8%
share of children whose eye drift improved to a mild level after patching plus therapy
n = 3,643 children
More results

The final review included 34 studies from 11 countries, comprising 3,643 children with a mean age of 5.70 ± 2.24 years.

“
Conclusion · 1 of 3

Multiple surgical and non-surgical options exist for managing childhood XT.

Conclusion · 2 of 3

Overminus lenses can improve distance control during testing, but deviation typically return to original state with non-overminus lenses, and their use requires monitoring for possible myopic progression.

Conclusion · 3 of 3

Surgery remains the primary treatment for constant XT, with bilateral lateral rectus recession and unilateral lateral rectus recession and medial rectus resection (R&R) showing similar short-term outcomes and long-term advantages for R&R.

Read paper
0 comments

No comments yet. Be the first.

Related papers

LatestFoundational
Cross-sectional
44.1%
had too much homocysteine in the blood, a far larger share than in dry AMD or healthy eyes
Cohort Study
92.3%
most laser-treated eyes had a favorable eye-structure outcome
Cohort Study
56%
lost three or more lines on the eye-chart vision test
Cohort Study
50%
older patients were more likely to lose three or more lines of vision
Study
81%
trials where mask air leaks were detected blowing toward the eyes
Cohort Study
13.5%
Central retinal artery peak blood-flow speed was 13.5% lower in diabetic patients.
Study
379 +/- 156 microm
lower thickness in the central retina, checked with an eye scan
Case Report
9 of 10 eyes
eyes had better measured vision after treatment