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New research · Ophthalmology
Survey of ophthalmology · 2d
ReviewSurvey of ophthalmology · 2026

Optical coherence tomography and angiography for the assessment of retinal microvasculature in retinopathy of prematurity patients: A systematic review and meta-analysis.

Masoumeh Mollapour Ballujeh, Razieh Asghari, Pedram Abdali … Mohammad Reza Abdol Homayuni
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OphthalmologyReview

Laser-treated retinopathy of prematurity eyes show higher foveal vascular density than term-born infants.

Optical coherence tomography and angiography for the assessment of retinal microvasculature in retinopathy of prematurity patients: A systematic review and meta-analysis.

Masoumeh Mollapour Ballujeh … Mohammad Reza Abdol Homayuni
Survey of ophthalmology · 2026
-9.29%
Results
-9.29%
Foveal capillary blood vessel density was about 9% higher in laser-treated eyes than in term-born infants.
n = 298 records
More results

Random-effects meta-analysis in R software computed pooled mean differences (MD) with 95% confidence intervals and heterogeneity (I²).

Similar patterns emerged for foveal DCP vascular density (MDs: -7 to -8%, P < 0.001).

Parafoveal SCP vascular density was higher in term vs. treated groups (MDs: 3-4%, P < 0.001).

More results

Laser-treated eyes had greater foveal thickness than regressed (MD: 35.5 µm, P < 0.001) and untreated retinopathy of prematurity (MD: 26.6 µm, P = 0.004).

“
Conclusion

OCT angiogropahy enables precise long-term monitoring to stratify visual risk in retinopathy of prematurity.

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