Ophthalmic Implications of Ehlers-Danlos Syndrome.
High myopia was more common in Ehlers-Danlos syndrome than in the general population.
Ophthalmic Implications of Ehlers-Danlos Syndrome.
Existing studies suggest an increased prevalence of many ophthalmic conditions as well as a higher rate of surgical complications, but a comprehensive understanding is lacking.
Ehlers-Danlos syndrome (Ehlers-Danlos syndrome) is a group of inherited connective tissue disorders with systemic manifestations, but its ophthalmic implications are poorly characterized.
Reported genetic and ophthalmic diagnoses, year of diagnosis, refractive error, and ophthalmic surgical history.
high myopia was much more common in Ehlers-Danlos syndrome than typical
Most respondents (83.3%) had hypermobile Ehlers-Danlos syndrome.
Dry eye, strabismus, amblyopia, blue sclera, and several other eye conditions were common and more prevalent compared to population estimates.
Several conditions, including glaucoma, posterior vitreous detachment, and retinal tear/detachment, presented at younger ages than expected.
Ophthalmic surgeries were overall well tolerated, although persistent postoperative pain was frequently reported.
Ehlers-Danlos syndrome may be associated with an increased risk and earlier onset of many ophthalmic conditions.
Several of these conditions, including glaucoma and retinal tear/detachment, could lead to significant morbidity if not detected and managed early. Ophthalmic procedures are well tolerated, but persistent pain is common.
Enhanced screening and tailored surgical management could improve quality of life in individuals with Ehlers-Danlos syndrome.