Post

New research · Ophthalmology
Journal of clinical medicine · 2d
Cohort studyJournal of clinical medicine · 2026

The Long-Term Evolution of Macular Retinoschisis in Eyes with Myopic Choroidal Neovascularization Treated with Anti-Vascular Endothelial Growth Factors.

Han-Hao Tsai, Fang-Ting Chen
Read paper
OphthalmologyCohort study

Baseline macular retinoschisis strongly predicts its progression after anti-VEGF treatment

The Long-Term Evolution of Macular Retinoschisis in Eyes with Myopic Choroidal Neovascularization Treated with Anti-Vascular Endothelial Growth Factors.

Han-Hao Tsai, Fang-Ting Chen
Journal of clinical medicine · 2026
Background

To investigate the structural changes and visual outcomes in eyes with myopic choroidal neovascularization (mCNV) treated with anti-vascular endothelial growth factor (anti-VEGF) compared with fellow eyes over a long-term follow-up period.

Methods

A retrospective paired-eye cohort study was conducted, and 51 patients (80.4% female, mean age 51.8 years) with an average follow-up duration of 32.8 months were enrolled.

n = 51 patients
Results

eyes with schisis at the start were far more likely to see it worsen

Baseline MRS present
70%
Baseline MRS absent
17.1%
“
Conclusion · 1 of 2

Anti-VEGF treatment in mCNV eyes did not increase the incidence of macular retinoschisis compared with fellow eyes or aggravate macular retinoschisis.

Conclusion · 2 of 2

However, the presence of macular retinoschisis at baseline may increase the risk of macular retinoschisis progression after treatment, and close monitoring of this subgroup is warranted.

Read paper
0 comments

No comments yet. Be the first.

Related papers

LatestFoundational
Cross-sectional
44.1%
had too much homocysteine in the blood, a far larger share than in dry AMD or healthy eyes
Cohort Study
92.3%
most laser-treated eyes had a favorable eye-structure outcome
Cohort Study
56%
lost three or more lines on the eye-chart vision test
Cohort Study
50%
older patients were more likely to lose three or more lines of vision
Study
81%
trials where mask air leaks were detected blowing toward the eyes
Cohort Study
13.5%
Central retinal artery peak blood-flow speed was 13.5% lower in diabetic patients.
Study
379 +/- 156 microm
lower thickness in the central retina, checked with an eye scan
Case Report
9 of 10 eyes
eyes had better measured vision after treatment